Panthers Game Sunday: Panthers vs Saints odds and prediction for NFL Week 2 game

(Jim Dedmon-USA TODAY Sports) Robby Anderson
(Jim Dedmon-USA TODAY Sports) Robby Anderson /

Week 2 of the 2021 season sees the Carolina Panthers go up against a familiar foe when they welcome the New Orleans Saints to Bank of America Stadium.

The Carolina Panthers are now turning their attention to their first divisional clash of the 2021 season against the New Orleans Saints at Bank of America Stadium. This has been a difficult matchup over the last couple of years, with Sean Payton’s men picking up two victories against their NFC South rivals in 2020 before faltering early in the playoffs once again.

Carolina comes into the game on the back of a 19-14 success versus the New York Jets to start the campaign. The Saints marked their first game in the post-Drew Brees era with a stunning 38-3 rout of the Green Bay Packers amid significant disruption to their preparations following the devastation of Hurricane Ida.

Although the Tampa Bay Buccaneers remain clear favorites to win the division in 2021 after their memorable Super Bowl triumph last time around, both the Panthers and Saints harbor ambitions to make the postseason despite the obvious questions surrounding them.

This is another good chance for the Panthers to make a statement. One that could lay another strong foundation to a successful 2021 campaign.

However, the Saints and their new quarterback Jameis Winston have other ideas.

Panthers vs Saints Odds Week 2

The Week 2 betting odds on WynnBET have the Saints as 3.0-point favorites on the road. They have -125 money line odds, while the Panthers are the underdog at +100.

The total for the game is set at an over/under of 24.0 points.

Panthers vs Saints Prediction Week 2

This will be a game of fine margins judging by what we saw in Week 1. Sam Darnold will look to make a statement against a team that might not be the force of old and without their star wide receiver Michael Thomas, although the New Orleans offensive line remains a real force to be reckoned with and they made light work of a fancied Packers team on Sunday afternoon.

Much has also been made of Winston’s unpredictability throughout his career, although sitting behind Brees has done him the world of good based on his first outing of the campaign.

That being said, with the Panthers being on home soil for a second straight week, they are tipped to overcome the Saints marginally by a score of 21-19 providing the offensive line can withstand what’s sure to be some significant pressure coming their way.

Make your pick now on WynnBET.

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