Carolina Panthers vs. San Francisco 49ers best bets for Week 5

The Carolina Panthers face another stern test of their credentials when the San Francisco 49ers visit Bank of America Stadium in Week 5.

Plenty of strong character will be needed from everyone within the Carolina Panthers in Week 5. The San Francisco 49ers represent another mammoth challenge for Matt Rhule and his roster, with another loss anticipated by many after such a poor start to the 2022 campaign.

Rhule knows he’s a man under pressure. There are rumors swirling about David Tepper’s patience running out, although the billionaire hasn’t declared his feelings one way or another publicly since shortly before the NFL Draft.

San Francisco’s No. 1 defense is going to be a tough task to overcome. Especially considering how poorly the Panthers’ offense has performed under the guidance of Ben McAdoo.

Fans aren’t expecting much from Carolina in this one. But this could help the team relax a little more in pursuit of attaining a much-needed victory to get themselves back in the hunt.

Carolina Panthers vs. 49ers injury report

The Panthers are dealing with some injury concerns to key men. Jeremy Chinn went to the reserve/injured list this week and his safety partner Xavier Woods could also miss the clash after suffering a hamstring complication.

Marquis Haynes and Frankie Luvu are questionable. Laviska Shenault Jr. has already been ruled out for the contest, which could mean more involvement for former second-round selection Terrace Marshall Jr.

Here is Carolina’s full injury report for Week 5:

• Laviska Shenault Jr. (WR) – Out (hamstring)
• Marquis Haynes (DE) – Questionable (knee)
• Frankie Luvu (OLB) – Questionable (shoulder)
• Stantley Thomas-Oliver III (CB) – Out (thigh)
• Xavier Woods (S) – Questionable (hamstring)
• Stephen Sullivan (TE) – Out (back)

Here is San Francisco’s injury report for Week 5:

• Arik Armstead (DL) – Out (foot)
• Tyrion Davis-Price (RB) – Out (ankle)
• Javon Kinlaw (DT) – Out (knee)
• Tyler Kroft (TE) – Out (knee)
• Colton McKivitz (OL) – Out (knee)
• Tarvarius Moore (DB) – Out (hamstring)
• Trent Williams (OT) – Out (ankle)

Carolina Panthers’ bets for Week 5

According to the latest odds from FanDuel Sportsbook, the Panthers are 6.5-point underdogs versus the Niners in Week 5. This can be bet at -110 in both directions (bet $110 to win $100).

Carolina currently stands at +230 on the money line (bet $100 to win $230), with San Francisco comfortably favored at -280 (bet $280 to win $100). FanDuel is not expecting this to be a thrilling game with an over/under of 39.5 points that can be wagered at -110 (bet $110 to win $100).

Game odds refresh periodically and are subject to change.

How to watch Carolina Panthers vs. 49ers in Week 5

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The game is also available to view on CBS.